2005 → 2026 · Cast then & now

Grey's Anatomy Cast: Then and Now

The cast then and now — with the original tribute song “Seattle Rain”.

1995

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About the series

Grey's Anatomy, then & now

Grey's Anatomy premiered in 2005, and ran for 22 seasons on American Broadcasting Company. This page follows Meredith Grey (Ellen Pompeo), Derek Shepherd (Patrick Dempsey), Cristina Yang (Sandra Oh), Alex Karev (Justin Chambers), Izzie Stevens (Katherine Heigl) then and now, with real ages, 10 then-vs-now collector’s cards in this tribute and the original tribute song “Seattle Rain”.

2005Premiered
22Seasons
10Characters in this tribute

The cast · 10 collector’s cards

Where is the Grey's Anatomy cast now (2026)?

The Grey's Anatomy cast then and now: 10 collector’s cards, 2005 vs 2026, with real ages. Tap a card to flip it and watch them walk side by side.

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The song

“Seattle Rain”

Sirens hum low on a grey city street
Read the lyrics

Sirens hum low on a grey city street
White coats and coffee, the sound of our feet
We were so young with a whole world to save
Learning to hold every life that we gave

And the pager still rings in the back of my mind
All the ones that we lost, all the ones left behind

Falling like the Seattle rain
Every heartbeat, every name
We were fire, we were flame
Still I'd do it all again
Through the long and lonely halls
We were catching each other's falls
Wash me clean and start again
In the sweet Seattle rain

On-call room whispers, the rooftops at dawn
Chosen like family, we carried each other on
Scalpels and secrets, the beat of the ward
Love in the chaos was our reward

And the pager still rings in the back of my mind
All the ones that we lost, all the ones left behind

Falling like the Seattle rain
Every heartbeat, every name
We were fire, we were flame
Still I'd do it all again
Through the long and lonely halls
We were catching each other's falls
Wash me clean and start again
In the sweet Seattle rain

Twenty years and the ghosts are still here
Some of us older, some disappeared
But the ones that we loved never really go
They live in the rain, in the faces we know

Falling like the Seattle rain
Every heartbeat, every name
We were fire, we were flame
Still I'd do it all again
In the sweet Seattle rain

Logged in to Spotify? You’ll hear the full song — otherwise a 30-second preview.

Stream “Seattle Rain” on Spotify

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Grey's Anatomy in numbers

The cast, then & now

Grey's Anatomy cast then and now, ages
CharacterActorThen (2005)Now (2026)
Meredith GreyEllen Pompeo35 56
Derek ShepherdPatrick Dempsey39 60
Cristina YangSandra Oh33 55
Alex KarevJustin Chambers34 56
Izzie StevensKatherine Heigl26 47
George O’MalleyT.R. Knight32 53
Miranda BaileyChandra Wilson35 57
Richard WebberJames Pickens Jr.50 72
Mark SloanEric Dane33 53 passed away
Callie TorresSara Ramirez30 51

Ages from verified birth dates, updated 02 November 2026.